蔗糖铁注射液治疗血液透析患者肾性贫血的临床观察

蔗糖铁注射液治疗血液透析患者肾性贫血的临床观察

郭齐;王群

【期刊名称】《河北医学》 【年(卷),期】2011(017)012

【摘要】Objective; To observe the efficacy and safety of intravenous iron sucrose in treating anemic hemodialysis patients. Method: Twenty maintenance anemic hemodialysis patients were given intravenous I-ron sucrose therapy. 100 milligram intravenous iron sucrose was given twice per week to every patients, the period of treatment was 5 weeks and the total dose of iron sucrose was 1000 milligram. The blood routine and serume ferritin (SF)were tested at the end of 0,2,6,8 week, C reactive protein(CRP) .ParathyroidHormone (PTH) 、alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were tested at the end of 0 and 8 weeks. The effective rate of anemia treatment was calculated at the end of 8 week. Result: Intravenous iron sucrose therapy significantly increased anemic hemodialysis patients' hemoglobulin (Hb) and he-motocrit (HCT). At the same time, intravenous iron sucrose therapy did not influence CRP、PTH、ALT or AST. Conclusion; Intravenous iron sucrose is effective and safe in treating anemic patients during hemodialysis.%目的:观察蔗糖铁注射液治疗血液透析患者肾性贫血的疗效与安全性.方法:选择20例规律血液透析的慢性肾功能衰竭中度贫血患者,给予每周2次、每次100 mg、总剂量1000 mg的静脉蔗糖铁注射液治疗.在患者入组前

及入组的第2、4、6、8周末测血常规、血清铁蛋白(SF),入组前和入组后8周时测C反应蛋白(CRP)、甲状旁腺激素(PTH)、谷丙转氨酶(ALT)与谷草转氨酶(AST)水平,并在8周末计算贫血治疗的有效率.结果:静脉输注蔗糖铁治疗后患者的血红蛋白(Hgb)、红细胞压积(HCT)、血清铁蛋白均明显升高,而CRP、PTH、ALT、AST均无明显变化.结论:蔗糖铁注射液治疗血液透析患者肾性贫血是有效且安全的.

【总页数】4页(1567-1570)

【关键词】蔗糖铁注射液;肾性贫血;血液透析 【作者】郭齐;王群

【作者单位】山东大学附属省立医院肾内科,山东济南250012;山东大学附属省立医院肾内科,山东济南250012 【正文语种】中文 【中图分类】 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_hebei-medicine_thesis/0201247315841.html 【相关文献】

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3.蔗糖铁注射液治疗血液透析患者肾性贫血的疗效观察(附39例分析) [J], 王四清; 徐维瑭; 郑秋风; 黄艳萍

4.蔗糖铁注射液治疗血液透析患者肾性贫血疗效观察 [J], 冯彬; 王煜华; 孙滨

5.蔗糖铁注射液治疗血液透析患者肾性贫血疗效观察 [J], 葛振华

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