多囊卵巢综合征伴或不伴亚临床甲状腺功能减退症患者内分泌代谢指

多囊卵巢综合征伴或不伴亚临床甲状腺功能减退症患者内

分泌代谢指标差异研究

谢艳妮;王娈;马瑞欣

【期刊名称】《中华内分泌代谢杂志》 【年(卷),期】2014(030)003

【摘要】Objective To compare the endocrine and metabolic parameters between patients suffering from polycystic ovary syndrome (PCOS) with or without subclinical hypothyroidism.Methods One hundred and fifty-six

PCOS

patients

and

47

healthy

controls

were

enrolled.Height,weight,waist circumference,and hip circumference were measured and recorded.Fasting blood samples were collected for measuring luteinizing hormone (LH),follicular stimulating hormone (FSH),total

testosterone,prolactin,estrogen,sex

hormone

binding

globulin (SHBG),thyroidstimulating hormone (TSH),free triiodothyronine (FT3),free thyroxine (FT4),blood glucose,serum insulin,triglycerides,total cholesterol,low-density lipoprotein cholesterol(LDL-C),and high-density lipoprotein cholesterol (HDL-C).Body mass index,waist-to-hip ratio,LH-to-FSH ratio,and free androgen index (FAI) were calculated.Homeostasis model assessment of insulin resistance (HOMA-IR) and β cell function (HOMA-β) were assessed.All patients underwent ultrasound for diagnosing polycystic ovary.All the patients were subdivided into two groups in terms of TSH value:subclinical hypothyroidism group with TSH