CGF联合骨代用品在即刻种植中修复种植体周围骨缺损的
实验研究
柳宏志;李超;王天祥;刘屹嵩;张立霞;邹高峰
【期刊名称】《口腔颌面外科杂志》 【年(卷),期】2012(022)004
【摘要】Objective: This study was aimed to evaluate the regenerative potential of concentrate growth factors(CGF) complex with bone substitute material in osteoinduction. Method: Twelve health hybrid dogs were used- Bilateral first mandibular premolars were extracted and BLB implants were installed immediately into the sockets. Bone defect (measured 2mm x4mm) was crealed in the distal aspect of each socket. Bone defect in both sides of the mandible were randomly divided into experiment or control groups. In experimental group, bone defects were filled with CGF complex and bone substitute material, in control group only bone substitute material were used. Every 4 dogs were killed at the end of 4、8 and 12 weeks respectively. Specimens were obtained and checked by X ray examination, scanning electric microscope observation, histological examination and survey the bone contact ratio (BCR). SPSS 11.5 was used. Results were statistically analyzed via one-way analysis of variance (ANOVA), with a significance level of P<0.05. Results: The experimental group manifested osseointegration process earlier than the control group, the healing lime of bone defect is also earlier than
CGF联合骨代用品在即刻种植中修复种植体周围骨缺损的实验研究
