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Successful transplantation of double unit umbilical-cord blood from unrelated donors in hi

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Successful transplantation of double unit umbilical-cord blood from unrelated donors in

high risk leukemia with a long follow-up

WANG Feng-rong;HUANG Xiao-jun;ZHANG Yao-chen;CHEN Yu-hong;LU Dao-pei

【期刊名称】《中华医学杂志(英文版)》 【年(卷),期】2005(118)009

【摘要】@@ Umbilical-cord blood (UCB) is a source of hematopoietic stem cells that has been successfully used for transplantation, primarily in children. But the low cell dose severely limits the application of unrelated umbilical-cord blood transplantation (UCBT) in adult patients, particularly in those with high body weight. We hypothesized that the combined transplantation of two partially matched UCB units would improve engraftment without crossed immunological rejection. Since May 2000, six adult patients with high risk leukemia have been transplanted in this study. 【总页数】5页(772-776)

【关键词】cord blood stem cell transplantation;unrelated donor;double;leukemia

【作者】WANG Feng-rong;HUANG Xiao-jun;ZHANG Yao-chen;CHEN Yu-hong;LU Dao-pei

【作者单位】Peking University People's Hospital,Institute of Hematology,Beijing

100044,China;Peking

University

People's

Hospital,Institute of Hematology,Beijing 100044,China;Peking University People's Hospital,Institute of Hematology,Beijing 100044,China;Peking University

People's

Hospital,Institute University

People's

of

Hematology,Beijing Hospital,Institute

of

100044,China;Peking

Hematology,Beijing 100044,China 【正文语种】中文 【中图分类】R73 【相关文献】

1.Risk factors of CMV infection in patients after umbilical cord blood transplantation: a multicenter study in China [J], Juan Tong; Zimin Sun; Huilan Liu; Liangquan Geng; Changcheng Zheng; Baolin Tang; Kaidi Song

2.Long-term outcomes in adults with leukemia treated with transplantation of two unrelated umbilical cord blood units [J], YIN Yue; REN Han-yun; CEN Xin-an; QIU Zhi-xiang; OU Jin-ping; WANG Wen-sheng; WANG Mang-ju; XU Wei-lin; WANG Li-hong; LI Yuan; DONG Yu-jun

3.Comparative outcomes between cord blood transplantation and bone marrow or peripheral blood stem cell transplantation from unrelated donors in patients with hematologic malignancies: a single-institute analysis [J], CHEN Yu-hong; XU Lan-ping; LIU Dai-hong; CHEN Huan; ZHANG Xiao-hui; HAN Wei; WANG Feng-rong

4.Successful second transplantation from haploidentical donor for graft failure following unrelated cord blood cell transplantation or mismatched related transplantation: 2cases report [J], XU Lan-ping; HUANG Xiao-jun

5.Human umbilical cord blood stem cell transplantation for the treatment of chronic spinal cord injury Electrophysiological changes and long-term efficacy [J], Liqing Yao; Chuan He; Ying Zhao; Jirong Wang; Mei Tang; Jun Li; Ying Wu; Lijuan Ao; Xiang Hu

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Successful transplantation of double unit umbilical-cord blood from unrelated donors in hi

Successfultransplantationofdoubleunitumbilical-cordbloodfromunrelateddonorsinhighriskleukemiawithalongfollow-upWANGFeng-rong;HUANGXiao-jun;ZHANGYao-chen;CH
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