肺结核合并乙肝患者抗结核治疗联合拉米夫定对药物性肝
损伤的影响研究
汤远钦;吴晓霞
【期刊名称】《中国社区医师》 【年(卷),期】2015(000)017
【摘要】目的：探讨肺结核合并乙肝患者使用拉米夫定联合抗结核治疗的临床疗效及对药物性肝损伤的影响。方法：收治肺结核合并慢性乙肝患者82例，随机分为对照组及观察组，各41例，观察组给予拉米夫定联合抗结核治疗，对照组给予抗结核治疗，对两组患者的肝功能及血清检测结果分析。结果：观察组肝功能及血清检验指标显著优于对照组(P＜0.05)；观察组不良反应发生率17.07%，明显低于对照组的48.78%(P＜0.05)。结论：肺结核合并乙肝患者采取拉米夫定联合抗结核治疗，可有效减少肝损伤，减少不良反应。%Objective:To explore the clinical curative effect and drug-induced liver
injury
influence
of
using
lamivudine
combined
with
antituberculosis treatment in pulmonary tuberculosis patients with hepatitis B.Methods:82 pulmonary tuberculosis patients with chronic hepatitis B were selected.They were randomly divided into the control group and the observation group with 41 cases in each.The observation group was given lamivudine combined with antituberculosis treatment.The control group was given antituberculosis treatment.The liver function and serum test results of patients in two groups were analyzed.Results:The liver function and serum test indexes of the
肺结核合并乙肝患者抗结核治疗联合拉米夫定对药物性肝损伤的影响研究
