辛伐他汀联合曲美他嗪治疗心肌梗死后心绞痛临床观察
孙瑞雪
【期刊名称】《中国实用医刊》 【年(卷),期】2016(043)003
【摘要】Objective To investigate the clinical effect of simvastatin combined with trimetazidine on angina pec-toris after myocardial infarction. Methods One hundred and five cases of angina pectoris after myocardial infarction pa-tients from October 2011 to October 2014 were selected,they were randomly divided into two groups,patients in control group adopted conventional drug treatment,and patients in observation group were treated with simvastatin and trimetazi-dine,the angina pectoris attack,total efficiency,the incidence of complications of two groups before and after treatment was compared. Results Before treatment,the angina attack frequency and duration time of two groups had no significant difference(P > 0. 05);After treatment,the angina attack frequency and duration time in observation group were significant-ly lower than those in control group,the differences were significant(P < 0. 05). The total effective rate in observation group was 92. 4% ,the rate of complications was 7. 5% ,3 cases of dizziness,1 case of blood ALT value increased but less than 2 times of normal value;the total effective rate in control group was 75. 0% ,the rate of complications was 5. 8% , 2 cases of dizziness,1 case of nausea. The
difference of the total effective rate of the two groups was significant( P <0. 05),but the rate of complications of the two groups had no significant difference(P > 0. 05). Conclusions Simvastatin combined with trimetazidine in treatment of angina pectoris after myocardial infarction can effectively reduce angina attack frequency and duration,intensive therapy effect,is a safe,reliable and feasible treatment scheme.%目的：探析辛伐他汀联合曲美他嗪治疗心肌梗死后心绞痛的临床疗效。方法选择襄垣县人民医院2011年10月至2014年10月收治的105例心肌梗死后心绞痛患者，随机分为两组，对照组采取常规药物治疗，观察组加用辛伐他汀与曲美他嗪进行治疗，比较两组治疗前后心绞痛发作情况、治疗总有效率及并发症发生率。结果两组治疗前心绞痛发作频率、持续时间比较差异未见统计学意义（P ＞0.05）；经治疗后，观察组心绞痛发作频率、持续时间均显著低于对照组，差异有统计学意义（P ＜0.05）。观察组治疗总有效率为92.4％，并发症发生率为7.5％，3例头晕、1例血丙氨酸氨基转移酶值增高但小于正常值2倍；对照组治疗总有效率为75.0％，并发症发生率为5.8％，2例头晕、1例心律失常，两组总有效率比较差异有统计学意义（P ＜0.05），并发症的发生率比较差异未见统计学意义（P ＞0.05）。结论辛伐他汀联合曲美他嗪治疗心肌梗死后心绞痛可有效减少心绞痛发作次数与持续时间，强化治疗效果，并发症少，安全可靠，为可行的治疗方案。 【总页数】2页(63-64)
【关键词】辛伐他汀;曲美他嗪;心肌梗死;心绞痛 【作者】孙瑞雪
【作者单位】046200 山西省襄垣县人民医院内科 【正文语种】中文 【中图分类】 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_chinese-journal-practical-medicine_thesis/0201255121541.html 【相关文献】
1.辛伐他汀联合曲美他嗪治疗心肌梗死后心绞痛临床观察 [J], 杨晓明; 杨智; 田爱丽
2.辛伐他汀和曲美他嗪联合治疗心肌梗死后心绞痛临床分析 [J], 万斯斯; 赵萍; 吴晓琼; 何优裕
3.探析辛伐他汀联合曲美他嗪治疗、心肌梗死后心绞痛的临床疗效 [J], 晏秀丽 4.曲美他嗪联合阿托伐他汀治疗心肌梗死后心绞痛患者的有效性与安全性分析 [J], 吴海军; 汪英男
5.阿托伐他汀联合曲美他嗪治疗心肌梗死后心绞痛临床观察 [J], 燕自仪; 李海亮
以上内容为文献基本信息，获取文献全文请下载
辛伐他汀联合曲美他嗪治疗心肌梗死后心绞痛临床观察
